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UID:4de65764e2b8da71c539eaff044ef294
CATEGORIES:Enseignements
SUMMARY:Analysis of NGS Data for Mendelian Traits
LOCATION:Berlin, Germany
DESCRIPTION;ENCODING=QUOTED-PRINTABLE:<p><strong>Identifying Genes for Mendelian Traits using Next Generation Seq
 uence Data</strong><br />September 18-22, 2017<br />Max Delbrück Center (MD
 C) for Molecular Medicine<br />Berlin, Germany<br />The Identifying Genes f
 or Mendelian Traits using Next Generation Sequence Data Course will be held
  at the MDC in Berlin from September 18-22, 2017. The goal of the course is
  to teach the course participants both theory and application of methods to
  identify pathogenic variants/genes for Mendelian diseases/traits using fil
 tering methods, homozygosity mapping and linkage analysis.<br />Emphasis in
  this course is on strategies for gene mapping and variant/gene identificat
 ion for Mendelian Traits. It will include theory as well as practical exerc
 ises. The exercises will be carried out using a variety of computer program
 s (e.g. Gemini, GeneHunter, GERP, Homozygosity Mapper, Integrative Genome V
 iewer, MERLIN, PhlyoP, Polyphen, SEQLinkage, Variant Mendelian Tools,). Top
 ics which will be covered at the course include: study design; linkage anal
 ysis and homozygosity mapping using genotype array and next generation sequ
 ence data (exome and whole genome), haplotype reconstruction, evaluating pe
 digree informativeness and power to detect linkage, vcf file annotation; ge
 neration of NGS data; identification of causal variants using filter approa
 ches, variant annotation, evaluation of deleterious effects of variants and
  their functionality. The organizers and instructors for the course are Suz
 anne Leal (Baylor College of Medicine) and Michael Nothnagel (University of
  Cologne).<br />Application Deadline June 12st, 2017<br />For a schedule, a
 pplication form and additional information please visit the course webpage.
 <br />https://statgen.research.bcm.edu/index.php/NGSMendelian2017</p>
DTSTAMP:20260410T111752Z
DTSTART;TZID=Europe/Paris;VALUE=DATE:20170918
DTEND;TZID=Europe/Paris;VALUE=DATE:20170923
SEQUENCE:0
TRANSP:OPAQUE
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